HTR1A and Familial prostate cancer: Compound AZ07 had the highest absolute cytotoxic activity against PC-3 prostate cancer cell lines (IC50 = 5.74 μM) and the 5-HT1A receptor agonist S14506 had the highest cytotoxicity against neuroblastoma SH-SY5Y cells (IC50 = 4.27 μM).