RET and medullary thyroid gland carcinoma: The medullary thyroid carcinoma (MTC) occurs in two forms: sporadic (75%) and hereditary (25%), in most cases with mutations in the proto-oncogene tyrosine-protein kinase receptor gene RET. Upon diagnosis, the most common treatment method of the disease is surgical intervention, including total thyroidectomy and central neck dissection, given that metastatic spread to cervical lymph nodes is a common event.