This means that we were unable to determine the mechanisms and implications of the sarcopenia we observed in overweight and obese adult women, especially if SO was found to be associated with altered inflammatory biomarkers (i.e., C-reactive protein) [19], which is known to play an important role in cardiovascular disease (i.e., myocardial infarction, stroke, peripheral vascular disease, coronary heart disease, and ischemic heart disease) [20]. The gene discussed is CRP; the disease is peripheral vascular disease.