Conversely, the cancer types with the smallest number of deregulated PRDM genes were SARC with no PRDM genes deregulated, PAAD with 1 gene upregulated (MECOM/PRDM3, FC = 2.71), THYM with two genes strongly downregulated (PRDM1, FC = 0.13 and ZFPM2/FOG2, FC = 0.16), CESC with two genes strongly downregulated (PRDM8, FC = 0.07 and ZFPM2/FOG2, FC = 0.04) and one gene strongly upregulated (PRDM13 FC = 29.86), and, finally, ESCA with two genes strongly downregulated (PRDM16, FC = 0.37 and ZFPM2/FOG2, FC = 0.44) and one gene upregulated (PRDM1, FC = 2.28). The gene discussed is MECOM; the disease is cancer.