CACNA1C and cardiac arrhythmia: The first report of a CACNA1C variant in isolated LQTS is due to Boczek et al. (2013), at which time the previously applied nomenclature LQTS type 8 was confirmed; and several further patients/families with LQT or other dysrhythmia have since been reported in the 2010s, as listed in Tables 3, 4, 5, 6, 7.