WT1 and Peritoneal Fibrosis: Conditional deletion of the Tgfbr2 gene in WT1+ mesothelial cells, treatment with the TGF-β1-blocking peptide p144 or p17, or use of mutant mice deficient in Smad3 all significantly attenuate the fibrotic response in (both) visceral and parietal mesothelium in several peritoneal fibrosis models153,155,159,160.