IL-25 can promote the expression of Th2 cytokines and accumulation of eosinophils [6, 26], inhibit the apoptosis of eosinophils, enhance adhesion between eosinophils and epithelial cells, release cytokines and chemokines by stimulating eosinophils, and thus promote allergy [2, 6, 36, 38, 39, 45, 53, 54]. The gene discussed is IL25; the disease is allergic disease.