Therefore, the search for new target molecules, including the transcriptional regulators and epigenetic modulators of tumor growth factors, has important clinical significance.22 In this study, we identified the overexpression of TdIF1 in NSCLC patient digital data by data mining of the TCGA database and validated this analysis in patient-derived tumor and adjacent normal tissue samples. Here, DNTTIP1 is linked to non-small cell lung carcinoma.