Analyses of murine and human cancers have shown that tumor-resident DCs consist mainly of three developmentally distinct subsets based on their expression of the CD64, MerTK, CD11b, XCR1, signal regulatory protein a (Sirpa), and CD103 surface markers: cDC1, cDC2, and monocyte-derived DCs (Mo-DCs)39. The gene discussed is XCR1; the disease is neoplasm.