It includes oncogenes—rearranged during transfection (RET) proto-oncogene and H-ras GTPase proto-oncogene (HRAS)—and several tumor suppressors: neurofibromin 1 (NF1), transmembrane protein 127 (TMEM127), and MYC-associated factor X (MAX). The gene discussed is NF1; the disease is neoplasm.