PLCG2 and autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation: Deletions of exons 19 or 20–22 cause cold urticaria and PLCγ2–associated antibody deficiency and immune dysregulation, PLAID [1, 2], while a point mutation (S707Y) is the basis of autoinflammation and PLCγ2-associated antibody deficiency and immune dysregulation, APLAID [3].