For an assay of the inhibition of KDM5B, we transfected KDM5B-specific small interfering RNAs (siRNAs) (siKDM5B#1 and #2) and negative control (siEGFP) into two HCC cell lines whose KDM5B expression were highly expressed, such as HepG2 and HuH7 cells (data not shown). Here, KDM5B is linked to hepatocellular carcinoma.