MYH11 and acute myeloid leukemia: Many chromosomal abnormalities are also observed in AML and produce molecular alterations by chromosome translocations, such as Runt-related transcription factor (RUNX) 1–RUNX1T1, Core-binding factor subunit beta (CBFB)–myosin heavy chain 11 (MYH11), promyelocytic leukemia (PML)–retinoic acid receptor alpha (RARA), and mixed lineage leukemia (MLL) fusions with various genes [5].