Furthermore, abnormal miR-122 can still be accumulated to cause the dysfunction of apoptosis through the dysregulation of TIMP1, and abnormal miR-29a can still be accumulated to cause the dysfunction of autoimmune through the dysregulation of IGF2, and abnormal miR-21 can still be accumulated to cause the dysfunction of metabolism through the dysregulation of ALDOB, which might facilitate tumor metastasis and invasion in HCC, as shown in Figure 4. The gene discussed is ALDOB; the disease is neoplasm.