19,20 The BRCA1-185 Ins-A mutation was also found in two of the previous studies that explored mutation in four ovarian cancer patients with Punjabi ethnicity.16,17 None of our selected samples revealed positive result for this mutation. The present study design has drawback of not including ovarian cancer patients for analysis of BRCA1 at exon 2. Here, BRCA1 is linked to ovarian cancer.