Wang and coworkers constructed an AD-associated lncRNA–miRNA–mRNA triple network based on the hyperphosphorylated tau theory by using 10 matched samples of NFT-harboring and normal neurons from the entorhinal cortex of mid-stage AD cases (Wang L.K. et al., 2017); by mapping the differentially expressed lncRNAs and mRNAs back to a global ceRNA network, the researchers constructed an AD NFT-associated ceRNA network containing 41 lncRNAs, 630 mRNAs, and 2,530 edges. Here, MAPT is linked to Alzheimer disease.