In the current study, HIF-2α levels measured in tissues were as follows: 49.11 ± 15.74 ng/mL in the control group, 71.082 ± 13.086 ng/mL in the CIN group, 44.881 ± 9.735 ng/mL in the CIN + SIL group, and 31.638 ± 6.448 ng/mL in the CIN + NAC group, respectively. The gene discussed is EPAS1; the disease is squamous cell intraepithelial neoplasia.