FUS and amyotrophic lateral sclerosis: Consistent with our findings in the hippocampal neurons (Figures 6E–6O and S6C–S6D), intra-axonal protein synthesis (revealed by decreased puromycin signal) was almost eliminated (Figures 7C–7D and 7F), along with increased accumulation of ALS-linked mutants of FUS (Figures 7D and 7G) within sciatic nerve axons of the two mutant FUS lines, but not their Non-Tg and hgFUSWT littermates.