Analysis of RTK expression in the ischemic cardiomyopathy samples revealed 3 RTKs with significantly enhanced expression (ROR1, KIT and TIE1) and 11 with significantly reduced expression (EPHA2, LTK, PDGFRB, ERBB3, FGFR2, AXL, ALK, ROR2, EPHA8, EPHB2 and EPHB4) when compared to healthy heart. The gene discussed is EPHB2; the disease is ischemic cardiomyopathy.