HMOX1 and chronic obstructive pulmonary disease: Interestingly, while cotreatment of hemin with QC‐15 prevented the rescue of mitochondrial respiration in COPD senescent fibroblasts, QC‐15 did not affect bioenergetic parameters and glycolysis (S4, data not shown), implying that the effect of hemin and HO‐1 induction is more specific toward modulation of mitochondrial function.