Although our previous work indicates that gain‐ or loss‐of PVT1 function affects gemcitabine efficacy in PC cells by transfection with full‐length PVT1 in the sense or antisense orientation, the role of the pvt1 locus remains unclear as a result of its encoded miRNAs (Beck‐Engeser et al., 2008; You et al., 2011). The gene discussed is PVT1; the disease is pachyonychia congenita.