In summary, they speculated that the secondary injury of chronic liver disease and the trigger mechanism for acute liver injury may lead to the expression of GP73.140 Wei et al found that the GP73 content in patients with chronic hepatitis C and HIV‐1 infection was significantly higher than that of healthy control group, and the increased GP73 was significantly correlated with body immune level and virus replication in HIV‐1‐infected patients. Here, GOLM1 is linked to chronic hepatitis C virus infection.