Because its relative molecular mass in polyacrylamide gel electrophoresis is 7.3 × 104, it is also called GP73.1, 2, 3, 4, 5, 6, 7, 8 At present, many studies have found that the GP73 protein is associated with liver diseases, especially with liver cancer diseases5, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23; therefore, it is expected to become a new serological tumour marker for early diagnosis of liver cancer, which has attracted widespread attention from research scholars. This evidence concerns the gene GOLM1 and liver disorder.