SET and breast carcinoma: When breast cancer cell lines MDA-MB-231, MDA-MB-436 and MDA-MB-468 were transfected with SET-targeted siRNA, CIP2A-targeted siRNA or scrambled siRNA, and then injected into the mammary gland of nonobese diabetic (NOD)/SCID/γ-chain null (NSG) mice, both SET knockdown and CIP2A knockdown reduced tumorigenic potential of breast cancer cell lines, compared with scrambled siRNA transfected cells (Janghorban et al. 2014).