Western blot assays validated the successful knockdown of Prx II in GR-shPrx II cells and showed that stemness was inhibited in GR NSCLC cells by Prx II knockdown, as observed by the reduced expression of CD133 and the stemness-related genes Nanog, Oct3/4, and Sox2 in GR-shPrx II, compared with GR-shCON cells (Fig. 1c). Here, SOX2 is linked to non-small cell lung carcinoma.