To explore if lysophospholipids such as LPC, which might be released during infection of epithelial cells with Salmonella, are involved in activating release of SipC from the pathogen, cells were treated with inhibitors of calcium independent phospholipase-A2 (iPLA2) and calcium dependent phosphoplipase-A2 (cPLA2) before infecting with S. Typhimurium. This evidence concerns the gene PLA2G6 and infection.