HNF4A and hepatocellular carcinoma: Furthermore, analysis of microarray data from human HCC (R2: Genomics Analysis and Visualization Platform, http://hgserver1.amc.nl/cgi-bin/r2/main.cgi) revealed heterogeneity in HNF4a transcript, with HCC displaying extremely high or extremely low levels of HNF4a mRNA compared to control tissue (Fig. 1f).