TAPSE, tricuspid annular plane systolic excursion; BMI, body mass index; bc, breast cancer; Hypertension, use of hypertension medication; ASA, low dose acetylsalicylic acid; Diabetes, use of diabetes medication; ACE angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; AI aromatase inhibitor use. The gene discussed is ACE; the disease is diabetes mellitus.