ANPEP and Alzheimer disease: Using 3-channel confocal microscopy, here we show that Aβ accumulates in > 30% of CD13+ and/or PDGFRβ+ pericytes on lectin+ brain endothelial capillary profiles (< 6 μm in diameter) in brain cortical sections from AD patients compared to barely detectable Aβ accumulation in pericytes in age-matched controls (see demographic Additional file 1: Table S1; Fig. 1a-f).