Analysis of the Hyperglycemia: Intensive Insulin Infusion In Infarction (HI-5) study showed that the ratio of serum glucose levels at the time of hospital admission, to average glucose levels during the prior 24 months, which also took into account patients prior history of diabetes, was associated with a higher risk of developing serious cardiac arrhythmias [37]. The gene discussed is INS; the disease is cardiac arrhythmia.