Rezk et al. [23] found that patients with the CC genotype and carriers of C allele of the rs2296545 renalase gene were significantly more likely to have prevalent CKD (CC genotype; OR: 4.84, 95%CI: 1.28–18.2, p = 0.02 and C-carrier; OR: 2.14, 95%CI: 1.07–4.26, p = 0.04). The gene discussed is RNLS; the disease is chronic kidney disease.