Indeed, according to the study conducted in the Yoruba tribe of Nigeria [29], two single APOL1 SNPs (rs73885319 and rs60910145) were significantly associated with CKD under all genetic models, with the largest effect under the recessive model (OR: 3.85 and 3.12 for rs73885319, and rs60910145, respectively). This evidence concerns the gene APOL1 and chronic kidney disease.