USP22 and colorectal carcinoma: Previously, we demonstrated that USP22 maintains stemness in CRC stem cells.23 To evaluate the effects of miR‐30‐5p on CRC cell stemness, we isolated CD133 + Caco2 and HCT15 cells using microbeads.23 As shown in Figure 3A, miR‐30‐5p was significantly downregulated in CD133 + Caco2 stem cells.