NR1H2 and prostate cancer: MYC is required for the activation of the majority of Wnt target genes in colon carcinogenesis.18 In agreement with our result, LXRβ activation controls MYC gene expression in colon cancer and prostate cancer.7, 19, 20 BMP4 expression level was also suppressed in colon cancer and MEFs after stimulation with an LXR agonist.21, 22 This suppression is associated with activation of Wnt signalling.23 Although a previous report showed that LXRβ interacts with β‐catenin in colon cancer cells,20 we did not detect direct interaction of LXRβ and β‐catenin in gastric cell lines.