HOTAIR and metastatic malignant neoplasm in the lymph nodes: In recent years, lncRNAs and miRNAs have been increasingly explored in their involvement with pathogenesis of gastric cancer.28 The HOTAIR investigated here was observed to be aberrantly expressed within breast cancer,9 gastric cancer,29 colorectal cancer,30 and pancreatic cancer tissues.31 The expressional level of HOTAIR also appeared a biomarker regarding the stages, lymph node metastasis, vascular invasion, and survival rate of gastric cancer patients,32 and our study also confirmed this part (Figure 1) (Tables 2 and 3).