CEACAM5 and colorectal carcinoma: For example, a large meta‐analysis of 4,055 patients undergoing intensive surveillance strategies demonstrated increased detection of disease recurrence and corresponding increased rate of curative surgery and increased survival.19 A prospective randomized study from the United Kingdom confirmed that either carcinoembryonic antigen (CEA) or computed tomography (CT) increased the odds of having a curative‐intent surgery, although there was no overall survival benefit of this strategy.14 Importantly, CRC surveillance has been found to be cost‐effective.21