In addition, in ApoE4 positive and ApoE4 negative PD paients with RBD, there was no difference in MoCA score loss (7.48 ± 11.04 versus 3.57 ± 11.05, P = 0.098) and Benton Judgment of Line Orientation (18.01 ± 25.03 versus 8.46 ± 29.13, P = 0.101). Here, APOE is linked to Parkinson disease.