With advances in next generation sequencing (NGS) and expression profiling studies, breast cancer is now understood as a collection of highly heterogeneous diseases with distinct clinical and molecular phenotypes (luminal A, luminal B, HER2-enriched and basal), each leading to unique clinical outcomes in terms of patients’ survival, disease progression rate, and treatment responses (Kalimutho et al., 2015). This evidence concerns the gene ERBB2 and breast carcinoma.