Among the TCR families expressed in CD8+ T cells mentioned above, Vβ9, Vβ16, Vβ18, and Vβ23 recognize dominant epitopes in BZLF1 and BMLF1 proteins, as well as in LCLs (42, 43); this observation confirms their relevance in the control of EBV infection and possibly in protection against the risk of virus-associated lymphomas. This evidence concerns the gene CD8A and Epstein-Barr virus infection.