In addition, there were four other high quality SNPs in non-coding RNA (including 1 micro-RNA: miR-27a; 3 long non-coding RNA: CASC8, CCAT2 and LOC105376400), which revealed that the aberrant expression of non-coding RNA could also be tightly related to CRC diagnosis [18–20]. This evidence concerns the gene CASC8 and colorectal carcinoma.