An integrated analysis of microarray-based mRNA expression profile and deep sequencing of noncoding small RNA of breast cancer cells (as described under “Experimental procedures”) led us to identify up-regulation of a serum- and glucocorticoid-regulated kinase gene (SGK1) and N-Myc downstream regulated gene 1 (NDRG1), along with down-regulation of miR-29a and miR-101-1, predicted to bind the 3′-UTR of SGK1, independent of the hormonal receptor status of the cells (Fig. S1A and Tables S1 and S2). The gene discussed is NDRG1; the disease is breast cancer.