BRCA2 and breast carcinoma: The BRCA1 and BRCA2 mutations are primarily responsible for hereditary breast cancer.31 Despite years of research, it has been shown that a minority of patients with a personal or family history of breast cancer have a genetic mutation as an identifiable cause.23 The present study is consistent with the global literature, as we have found a positive association of family history with the development of the disease (p = 0.004).