Unlike other members of the family, MELK is not related to cellular energy metabolism balance.9 MELK is highly expressed in a wide range of malignant tumors, including hepatocellular carcinoma,10 breast cancer,11 melanoma,12 acute leukemia,13 ovarian cancer,14 neuroblastoma15 and myeloma.16 It is actively involved in cell cycle regulation, proliferation, apoptosis, and tumor formation.9,17 However, the role of MELK in cervical cancer has not been elucidated. This evidence concerns the gene MELK and hepatocellular carcinoma.