The top 10 candidate pathways identified by the STRING tool were one carbon pool by folate (P value = 1.60 × 10‐16), aminoacyl‐tRNA biosynthesis (P value = 4.64 × 10‐13), metabolic pathways (P value = 2.07 × 10‐7), cell cycle (P value = 1.27 × 10‐7), TGF‐beta signaling pathway (P value = 4.64 × 10‐6), bladder cancer (P value = 1.71 × 10‐5), purine metabolism(P value = 2.75 × 10‐5),non‐small cell lung cancer (P value = 5.95 × 10‐5),pancreatic cancer (P value = 7.72 × 10‐5),glioma(P value = 7.72 × 10‐5). The gene discussed is TGFB1; the disease is lung cancer.