ALK and non-small cell lung carcinoma: ALK-translocated NSCLC is found mostly in younger patients with adenocarcinoma histology and a history of never or light smoking (Inamura et al., 2009; Koivunen et al., 2008; Perner et al., 2008; Shaw et al., 2009; Takeuchi et al., 2008; Wong et al., 2009).