DNER and cancer: A less stable but more commonly studied BET inhibitor, JQ1 ((S)-tert-butyl2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3a][1,4] diazepin-6-yl)acetate), is particularly effective against BRD4 and has been shown to downregulate c-MYC, an oncoprotein involved in cell proliferation and cancer pathogenesis [6].