The subpopulation of ALDEFLUOR-positive (ALDH activity–positive) cells was 26.8% among control HSC-4 cells but was only 0.2% or 1.3% among HSC-4 cells treated with the reversible ALDH inhibitor diethylaminobenzaldehyde (DEAB) or with dyclonine, respectively (Figure 2C), suggesting that dyclonine indeed acts as an ALDH inhibitor in cancer cells. Here, LDHA is linked to cancer.