When the drug transporter (MDR-1 (Pg-1), MDR-2, MDR-3, MDR-4, MDR-5, BCRP, MDR-1 and LRP) mRNA expression in tumor region, determined by RT-qPCR, as presented in Figure 2B, all ATP-binding cassette proteins as well as lung resistant protein were detected. The gene discussed is ABCB4; the disease is neoplasm.