Increased CAV1 expression has also been observed in a series of drug-resistant cancer cells compared with their parental cells such as paclitaxel-resistant A549 cells, vinblastine-resistant SKVLB1 cells, colchicine-resistant HT-29 cells, and adraimycin-resistant MCF-7 cells (Lavie et al., 1998; Yang et al., 1998). The gene discussed is CAV1; the disease is cancer.