A prolongation of the cardiac action potential and the QT interval on the surface electrocardiogram (ECG) has been associated with loss of function mutations in hERG (Yang et al., 2009; Sun et al., 2013; Zhang et al., 2013) or drug-trapping inside the central cavity of the hERG potassium channel and thus, may predispose to life-threatening ventricular tachyarrhythmia “Torsade-de-points” (TdP) (Roden, 2004; De Bruin et al., 2005). The gene discussed is KCNH2; the disease is torsades de pointes.