Although we did not observe improvement in triacylglycerol levels, some authors report that increased incretin plasma concentration is related to the reduction of intestinal absorption of triacylglycerol in animal studies34, besides Vildagliptin be able to lowers triacylglycerol-rich lipoprotein postprandial levels in T2DM, suggesting that DPP-4 inhibitors mobilize and burn fat during meals, and thus the fat that is associated with cardiovascular risk is not accumulated35. This evidence concerns the gene GCG and type 2 diabetes mellitus.