As observed in this research, some prior results reported that DPP-4 inhibitors and Quercetin may reduce glycemic variations in the diabetes model12,13, however clinical trials and other research in T1DM indicate that administration of each of these agents separately is not consistent in altering glycemic parameters8,14, that is, results are conflicting and the final outcomes are inconclusive. The gene discussed is DPP4; the disease is type 1 diabetes mellitus.