The results from Table 3 showed that before TPN treatment, the plasma protein level in the two groups of patients did not differ significantly, while after TPN treatment, the albumin, prealbumin and the total protein content of the TPN-treated patients in SPN group were higher than that of IPN group, and all three proteins had significant difference (p < 0.01). This evidence concerns the gene TTR and bile duct papillary neoplasm.